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Brand Name :

(Losec) ®

Dosage form :

20 mg Capsule.

Indication :

Short-term (4-8 weeks) treatment of severe erosive esophagitis (grade 2
or above), diagnosed by endoscopy and short-term treatment of
symptomatic gastroesophageal reflux disease (GERD) poorly
responsive to customary medical treatment; treatment of heartburn;
pathological hypersecretory conditions; peptic ulcer disease; gastric
ulcer therapy; maintenance of healing of erosive esophagitis; approved
for combination use in the eradication of H.pylori in patients with
active duodenal ulcer.

Dosage :

Adults: Oral: Active duodenal ulcer: 20 mg daily for 4-8 weeks.

GERD or erosive esophagitis: 20 mg daily for 4-8 weeks. Pathological
hypersecretory conditions: 60 mg once daily to start; doses up to 120
mg 3 times daily have been administered; administer daily doses >80
mg in divided doses.

Helicobacter pylori: Combination therapy with bismuth subsalicylate,
tetracycline, and clarithromycin; or with clarithromycin alone.

Adults: Oral: 20 mg twice daily.

Gastric ulcer: 40 mg daily for 4-8 weeks.

Warning / precaution :

Adverse reactions :

Headache, rash, diarrhea, weakness, back pain, cough, upper respiratory
infection, agranulocytosis, alopecia, benign gastric polyps,
gastroduodenal carcinoids.

Therapeutic class :

Medication safety issues :

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